Dean Fisher received his Bachelor of Science degree in mortuary science from the University of Minnesota in 1984. He worked in the funeral service community until joining Mayo Clinic as a licensed funeral director in the Department of Anatomy in 1988. He coordinated the "Anatomical Bequest Program" for the department and was active in other departmental and institutional activities, including serving as chair of the Deceased Patient Work Group. He was named an Associate in the Department of Anatomy by the Mayo Board of Governors in 2001.
He assisted in the research and development of the Alkaline Hydrolysis process while at the Mayo Clinic and has given numerous presentations on this technology in the United Kingdom, Canada, and the United States. In 2017 he moderated the first Alkaline Hydrolysis Summit in the world at the CANA Symposium in Las Vegas. He served for 6 years as a board member of the Cremation Association of North America (CANA).